Search results for "Annona glabra"

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Acetogenins from Annona glabra seeds

1998

Abstract From the cytotoxic ethanol extract of Annona glabra seeds, a new mono-tetrahydrofuranic (mono-THF) acetogenin, glabranin, as well as pair of 22-epimer bis-THF acetogenins, were isolated by semipreparative HPLC. Four known mono-THF acetogenins with an identical threo/trans/threo relative configuration, annonacin, annonacinone, corossolin and corossolone, were found to be potent inhibitors of complex I of the mitochondrial respiratory chain.

chemistry.chemical_classificationbiologyStereochemistryAnnonacinRespiratory chainPlant ScienceGeneral MedicineHorticultureCorossolonebiology.organism_classificationBiochemistrychemistry.chemical_compoundMitochondrial respiratory chainchemistryAnnona glabraAnnonaceaeAcetogeninMolecular BiologyLactonePhytochemistry

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